工作职责:As a medicinal chemistry leader, drive and direct medicinal chemistry functions for one or more drug discovery projects. The main job functions include:? Working in concert with partners in molecular and cellular biology, pharmacology, molecular informatics, ADME, structural biology, chemical development, and other key functions;? Analyze screening data, perform literature reviews, design, propose, and execute medicinal chemistry plans, coordinate chemistry and biology data to support compound progression and patent strategies;? Involved in supervising and/or directing synthetic chemistry activities internally;? Participate in shaping and implementing strategies that support Medicinal Chemistry growth objectives;? Serve as a scientific expert in medicinal chemistry and provide recommendations regarding new targets and emerging external opportunities;? Ensure optimal interaction/communication and provide updates on project status to the client.任职资格:? PhD in synthetic or medicinal chemistry is required, preferably with postdoctoral experience? At least 8 years of experience in the biotechnology or pharmaceutical industry with a proven track record of innovative projects and key contributions to clinical candidate selection.? Prior project leadership is required? Broad experience and proven accomplishments in a field of Medicinal Chemistry, preferably in one or more fields of oncology, immunology and virology, with operational skills for managing discovery programs at the level of a team leader and a proven track record of delivering clinical candidates is much desirable.? Candidates will have a track record of successful contributions to, and leadership of, innovative drug discovery projects, exemplified by a record of patent inventorship, conference presentation and peer-reviewed publication.? Expert knowledge of modern methods of synthetic and medicinal chemistry with ability to successfully and simultaneously conduct medicinal chemistry on multiple projects is required? Solid understanding of cellular /molecular biology, biochemistry, disease pharmacology, mechanisms of drug metabolism and molecular toxicology, pharmaco-kinetic and pharmaco-dynamic sciences, and the formulations for the in vivo evaluation of drug candidates is required? Strong knowledge of computational chemistry methods and working knowledge of biophysical methods ? Experience in leading multi-disciplinary, cross-functional teams to advance projects, with involvement in supporting cross-company/external collaborations or partnerships is preferred? Ability to integrate multiple R